Alcoholic residues are highlighted in blue, acidic residues in green, and aromatic residues in red
As part of the Nobel Prize celebration, each Nobel laureate delivered a lecture on their respective areas of expertise
Tirzepatide (GLP-1 + GIP): This is a newer, dual-action medication and the same active ingredient as Mounjaro and Zepbound
3,507 GLP-1RAs reduce liver fat accumulation by activating AMPK, which inhibits fatty acid synthesis enzymes and promotes fatty acid -oxidation, thus diminishing lipid droplet accumulation in hepatocytes
Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS, Lazar MA (2001) The hormone resistin links obesity to diabetes
Clinical trials and post-marketing surveillance have identified a modest increase in resting heart rate as a potential effect of GLP-1 receptor agonists