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doi: 10.3389/fnbeh.2023.1185522 4 SudaKMatsudaK
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When the BBB is destroyed, plasma protein leakage increases, causing protein retention and leading to adverse effects on the nervous system [40]
For example, abdominal obesity may contribute to insulin resistance and inflammation, aggravating hypertension, while insulin resistance may directly impact blood vessel function, further worsening hypertension (Kawai et al., 2021)
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