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## Head-to-Head Comparison: AOD-9604 vs Semaglutide ### Clinical Evidence for Weight Loss This is where the comparison becomes decisive

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doi: 10.1016/j.phrs.2025.107706 72

(See Figure 1) FIGURE 1 2.2 Cisplatin induces oxidative stress The cochleas high metabolic rate results in its production of abundant reactive oxygen species (ROS), so it requires an active antioxidant defense system [glutathione (GSH), oxidized glutathione (GSSG), and antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR)] to achieve a dynamic oxidant-antioxidant balance to maintain healthy hearing

Semaglutide (The Active Ingredient in Ozempic and Wegovy) Semaglutide was the medication that launched the GLP-1 weight loss revolution

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