For the dataset of the tirzepatideGIPRG s Nb35 complex, automated particle selection yielded 4,260,187 particles, which were subjected to reference-free 2D classification, producing 1,771,599 particles with well-defined averages
Moreover, long-acting GLP-1 RAs have been approved for the treatment of obesity due to their improved tolerability, safety, and efficacy ( Introduction , previous investigations into GLP-1 RA-related AEs primarily concentrated on gastrointestinal- and tumor-related issues
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doi: 10.1002/eji.201343316 168 HashimotoAHayashiIMurakamiYSatoYKitasatoHMatsushitaRet al
Eur J Pharmacol 730:2630