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Combination therapies are expected to improve efficacy, tolerability and muscle preservation, while new indications such as cardiovascular disease, MASH and chronic kidney disease continue to broaden the commercial potential of the incretin class

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Guirguis says combination treatments such as this could offer additive or synergistic effects meaning that patients have a better chance of responding to at least one of the mechanisms and could experience fewer GI side effects as a result of the dual approach

If you miss a meal or the meal contains no fat, skip the Orlistat dose

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Third, applying the method in the microplate reader is challenging due to the requirement for protein precipitation