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Multi-omics studies revealed that SARS-CoV-2 infection provokes significant changes in numerous metabolites including those impacting on virus propagation (one-carbon metabolism) and GSH synthesis (amino acids glutamic acid, cysteine and glycine) that could be used as early prognosis biomarkers in COVID-19 at diagnose to predict severe COVID-19 and LONG COVID (Doan et al., 2021

Lancet 402 , 429431 (2023)

GPX8 can inhibit the oxidative stress response of hepatocellular carcinoma cells ( A great deal of research on the structure and function of GPX in mammals has helped us understand the essential functions of this class of proteins

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