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Cancer cells utilize glutamine metabolism-related branched pathways involved in the development of drug resistance Glutamine synthetase (GS), an enzyme that functions at the origin of glutamine metabolism, is the sole regulatory factor that governs glutamine synthesis from its fundamental stages, thereby playing a pivotal role in the progression of cancer [213]

K., & Pandey, S

2530, 1997 [13] W

The coordinates of NTSR, G i , and scFv16 from the structure of the neurotensin-NTSR-G i -scFv16 complex (PDB ID 6OS9) were used as initial models to dock into the cryo-EM maps using Chimera 48

elastin, proteoglycans, and glycosaminoglycans production

The affected domains included cell survival, cytokine release and oxidative stress