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I'm just wondering what evidence you have for this
As a result, this alteration stops Nrf2 from being ubiquitinated, which allows it to go into the nucleus and attach to antioxidant response elements (ARE) found in the promoter regions of antioxidant genes to increase their production
The literature also describes upregulation of growth factors involved in tissue repair, modulation of nitric oxide synthase activity, and effects on the dopaminergic and serotonergic systems that are harder to interpret clinically [Sikiric et al., Inflammopharmacology, 2018]
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