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While pathway analysis identified metformin and certain combination therapies as strong candidates for preventing DM2-associated AD by modulating key pathways, MR analysis found no evidence supporting a causal protective relationship between genetically proxied metformin effects and AD risk
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doi: 10.1016/j.neuropharm.2013.04.008 78 DAmicoMDi FilippoCMarfellaRAbbatecolaAMFerraraccioFRossiFet al
This hormone signals your brain that you are full, helping reduce appetite and food intake
