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doi: 10.3390/jcm10030441 20 McIlroyGDSuchackiKRoelofsAJYangWFuYBaiBet al
[15] In both trials, after 72 weeks of treatment, participants who received tirzepatide at all three dose levels experienced a statistically significant reduction in body weight compared to those who received placebo, and greater proportions of participants who received tirzepatide achieved at least 5% weight reduction compared to placebo
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Notably, eight taxa at the genus level were significantly abundant in the TMAO-producer group (FDR 10 M) that grouped to low producers after carnitine supplementation