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It is based on the native GIP sequence with modifications that enable cross-reactivity at the GLP-1 receptor, plus a C20 fatty diacid chain attached via a linker for albumin binding (half-life approximately 5 days)

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IgM-mediated autoimmune responses directed against anchorage epitopes are greater in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) than in major depression

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