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The most common causes of sudden onset are post-inflammatory hyperpigmentation from a minor injury (biting, burning food, allergic reaction to a product), a small blood blister or hematoma from trauma, or a venous lake forming under the surface

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Last, our previous studies confirmed that LPS enhanced Ca 2+ influx, as mediated by TRPA1 in OA-FLS [24]

Always consult a qualified healthcare provider before starting peptide therapy