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"You rebound the fat mass much faster than muscle, so you actually start impinging pretty heavily on lean muscle if you go through multiple rounds of these cycles," Pye said at the Biotech Showcase panel

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[16] [17] Currently, there are no specific FDA-mandated bone density monitoring requirements for patients prescribed GLP-1 receptor agonists, as these medications have not been definitively linked to increased fracture risk or clinically significant bone loss in regulatory reviews

Mild side effects, such as soreness at the injection site, are rare