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NHS England (2021) National diabetes audit, 2020-21 type 1 diabetes
By eliminating senescent cells in preclinical systems, FOXO4-DRI indirectly reduces the source of SASP factors
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Combined with our trafficking and insulin release results, these data show a canonical role for -arrestin recruitment in promoting GLP-1R endocytosis and desensitization
We need some of these radicals because they can act as signaling molecules that trigger important processes (like the heart pumping more blood during stressful moments)
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