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Overall, most studies had point estimates located to the right of the null line (OR = 1), indicating a higher incidence of depressive events in the GLP-1 RA group compared with the control group

Potential Side Effects of Shifting Your Schedule When you take your Wegovy shot a day early, the most significant risk is not a lack of efficacy, but rather a temporary increase in side effects

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If your genetic profile shows lower GLP-1 receptor sensitivity or variants associated with stronger hunger signals, you're likely among those who experience rapid rebound after discontinuation

Doctors can sometimes prescribe medications off-label, meaning outside the FDA-approved uses listed on the label