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Adaptive designs, umbrella and platform trials, and master protocols offer a path forward, but they are not without obstacles
Additional analyses of the early MACE separation for semaglutide versus placebo by individual MACE components, additional clinical outcomes, patient subgroups, and other parameters changing during the early post-randomisation stages of the trial will be provided, the authors note
While its prescribed for medical conditions, using it for muscle growth is considered off-label and may be subject to stricter laws
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