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130(6): 5816 Baldelli R, Battista C, Leonetti F, et al
MitoSOX fluorescence was increased in Fabry kidney organoids but was decreased after ERT (Fig
Future research should focus on translating these promising results into human trials to validate their efficacy and safety in diverse patient populations
The pharmacological reality of peptide degradation in the GI tract makes meaningful oral absorption extremely unlikely without specialized encapsulation technology (which is still largely experimental for peptides of this size)
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