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One should consider the primary phase lesion and hemorrhaging that results from mechanical damage during SCI as well as the secondary phase lesion that lasts several hours or even several months and is accompanied by edema, hemorrhage, inflammation, and cytotoxic edema [44,45,46,47] and may extend to the white matter area and lead to white matter degeneration and damage [48, 49]

side effects are generally mild [14]

Research conducted on rats showed that this synthetic peptide can counteract the effects of cuprizone, a drug that induces demyelination of nerve fibers and mimic the damage caused by multiple sclerosis, by reducing nerve damage [10]

Pharmacokinetic parameters were evaluated using the WinNonlin software (version 5.3) according to a non-atrioventricular model

Closest-analog combination data

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