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The primary actions of secretin include induction of bile secretion from the gallbladder into the duodenum, enhanced secretion of bicarbonate and H 2 O into the duodenum from the pancreas, and increased gastric pepsin secretion
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(3) This may involve the activation of an intracellular messenger called cyclic AMP (cAMP) and the kinase PKA (protein kinase A), which together may switch on the cellular machinery that moves growth-hormonecontaining vesicles to the membrane for release
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