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It has been shown that GLP-1RA semaglutide can improve working and spatial memory in transgenic AD modelling APP/PS1/tau (3xTg) mice, promote the release of anti-inflammatory factors and inhibit the production of pro-inflammatory factors in the cerebral cortex and hippocampus, as well as reduce the deposition of -amyloid in the CA1 subfield of the hippocampus
Sanchez-Yus E, Requena L, Simon P, et al
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Front Cell Neurosci 17:1101379
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Deng Z, Fan T, Xiao C, Tian H, Zheng Y, Li C, et al
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