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After 4 weeks of 0.25 mg, increase dose to 0.5 mg once weekly
Key Takeaway: Used off-label primarily for patients who plateau on GLP-1 alone Are Mood Effects Something to Watch For
In addition to fertility, GLP-1 drugs influence on testosterone may also benefit general male health, including muscle mass, mood, and energy levels, suggesting wider systemic benefits
Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose of NN2211, a long-acting glucagon-like peptide 1 derivative, in healthy male subjects
10.1126/science.8456284 33 ForristallC
As AUD is a heterogeneous disorder with a multifaceted pathophysiology, the possibility that combinations of GLP-1 and other gutbrain axis peptides synergistically reduce alcohol drinking should be explored in future studies
