Low magnesium levels can manifest as fatigue, muscle weakness, and even muscle cramps symptoms that might be incorrectly attributed solely to semaglutide side effects
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10.1172/jci.insight.160702 132 SalahuddinA.AshrafA.AhmadK.HouH
As demonstrated by published real-world evidence and current NICE guidance, it is rare for GLP-1 receptor agonists to be indicated or prescribed as second-line or even third-line treatment options in the UK, despite European-wide guidelines published by the European Association for the Study of Diabetes indicating SGLT-2 inhibitors and GLP-1 receptor agonists as equal second-line options, particularly for people with established or high risk of cardiovascular disease.1214 58 The present study was therefore designed to answer a different research question for the UK setting, specifically whether immediate oral semaglutide initiation could improve health outcomes for people with type 2 diabetes while providing value for money for the NHS
As of May 2024, about 22% of adults who had been told by a doctor that they are overweight or obese said they had ever taken a GLP-1 drug, according to a KFF poll
The medication has thus emerged as a valuable tool in the fight against obesity, offering a scientifically-backed option for sustained weight management