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[21] Traverso, N., Ricciarelli, R., Nitti, M., Marengo, B., Furfaro, A.L., Pronzato, M.A

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doi:10.1111/j.1532-950x.2003.00515.x

An RCT of 174 patients with severe alcoholic hepatitis found that the combination of prednisolone + NAC (IV for 5 days, then oral for 2 weeks) significantly reduced 1-month mortality compared to prednisolone alone (8% vs 24%, p=0.006), though the difference was not significant at 6 months (Nguyen-Khac et al., N Engl J Med, 2011) [36]