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Hypertension 63 , 827838 (2014)
Koek, G
Carnitine membrane transporter deficiency: a long-term follow up and OCTN2 mutation in the first documented case of primary carnitine deficiency
Also levels of cleaved PARP (PolyADP ribose polymerase) 42 were detected with the appearance of a 90 kDa lower band as opposed to 113 kDa uncleaved PARP in GNE knockdown cells indicative of DNA damage (Fig
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Because the milligram amount is fixed, a lighter body gets more drug exposure per pound: roughly 22% more at 70 kg and about a third less at 120 kg, compared with a 90 kg reference. The dose still comes from response and tolerability, but a lighter person is running a hotter exposure at the same number on the vial
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