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n = 5) relative to normal C57BL/6J mice (21 1 fmol/mg protein

4 Physiotherapy Programme, School of Rehabilitation Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia Background: Frailty is a biological syndrome of decreased reserve and resistance to stressors due to decline in multiple physiological systems

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Concurrently, improved insulin sensitivity suppresses adipose tissue lipolysis and reduces circulating free fatty acid concentrations [57]