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Therapeutic interventions for aging: the case of cellular senescence

Furthermore, when apoptosis and necroptosis fail to occur, caspase-8 can be involved in the activation of caspase-1 and inflammasome to trigger pyroptosis, a strongly proinflammatory cell death modality associated with the release of IL-1 and IL-18 [145, 146]

10.1186/s13020-024-00959-1 97 PawlakA.GewartowskaM.PrzybylskiM.KuffnerM.WiligrskaD.GilR.et al (2022)

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