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Reduce the risk of cognitive decline and Alzheimers disease (11) Treat pernicious anemia, a condition that can cause nerve damage and increases your risk of stomach cancer (12)

Its molecular target is nicotinamide N-methyltransferase (NNMT), a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, consuming SAM and releasing S-adenosylhomocysteine

Symptoms of an allergic reaction may include swelling, rash, or difficulty breathing

Published online June 27, 2014