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The combination could theoretically increase gastrointestinal side effects by amplifying the impact on gastric emptying
A popular dual agonist, tirzepatide (Mounjaro), activates both GLP-1R and GIPR, producing synergistic effects on insulin secretion, appetite suppression, and weight reduction (Table 1)
doi: 10.1128/AEM.72.2.981-985.2006 38 KimS.-E.KimS
This could be a potential problem if you already have high levels of iron in your body
greater degree of weight loss is seen when initiating from a higher starting weight [42]
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