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Cellular nitric oxide production in vascular endothelial cells was detected by the emitted fluorescence from DAF-FM DA probe upon the interaction with nitric oxide

115 MariM.CaballeroF.ColellA.MoralesA.CaballeriaJ.FernandezA.et al (2006)

However, interpreting the direct impact of gut-derived neurotransmitters on CNS function requires caution, as most peripheral neurotransmitters cannot freely cross the BBB under homeostatic conditions [187]