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When to seek medical advice Contact a GP promptly if symptoms are persistent, worsening or unexplained, especially if you have numbness, pins and needles, balance or walking problems, weakness, memory changes, breathlessness, palpitations or vision changes

Seizure medications such as phenytoin and phenobarbital, as well as diabetes medications like metformin, can lower B12 levels over time

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The symptoms mentioned have for the most part evaporated

5-Amino-1MQ is studied for its proposed NNMT inhibition properties, with downstream research interest in NAD+ pathway and SIRT1 signalling modulation, while Methylene Blue is studied for distinct redox and electron-transfer properties relevant to mitochondrial pathway research

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