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The evidence is clear: for most patients, high-dose oral supplements are as effective as injections
In all the five studies, an oral (Delpres study via sublingual route) dose of 1000 g vitamin B 12 was used with the exception of Kuzminskis study, whereby a higher dose of 2000 g was used
Adjustments are often needed based on how a patient responds and lab results
doi:10.1038/s41598-024-65310-y Neelakantan H, Hommel JD, Watowich SJ, et al
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