Observational Studies & RealWorld Data These are large database studies, often with millions of patients, comparing dementia incidence (or cognitive decline) among people with T2DM (or obesity) using GLP-1 RAs vs other therapies
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H.PetrovicA.et al (2020b)
TRANSCEND-T2D-1 also reported improvements in non-HDL cholesterol, triglycerides, and systolic blood pressure, but these are risk markers rather than proof of fewer heart attacks, strokes, kidney outcomes, or heart failure events [9]
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however, helping them understand their disease on a metabolic level can reduce the self-blame and shame that tends to only worsen their outcomes overall