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Prognosis [edit] No adverse effects or consequences of melanosis coli have been identified

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The transcription factors ATF4 and Nrf2 couple ER stress to a general cellular response that increases the production of glutathione by increasing aminoacid metabolism (Cullinan et al , 2003

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Dzce niv Bil Teknol Derg 9:4050 Trd L, Janda M, Mackov D, Pospchalov R, Dobrev PI, Burketov L, Matuinsky P (2019) Dual mode of the saponin aescin in plant protection: antifungal agent and plant defense elicitor