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It is important to highlight that elderly persons are at notable risk of the medication overload that elevates the likelihood of APAP exposure 18 , the compromised liver function that facilitates accumulation of toxic metabolites 19 , and the aging-associated disorders, such as Alzheimers disease (AD), that elevate the brains susceptibility to and severity of dyshomeostasis events 20

You can have the best delivery truck fleet in the world, but if there are no goods to deliver (fatty acids mobilized by a proper diet) and no destination demanding them (energy expenditure from activity), the trucks just sit idle