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In clinical practice, SGLT2 inhibitors are often initiated first due to their oral administration and broader reimbursement, with GLP-1 receptor agonists subsequently added to address persistent hyperglycemia, excess body weight, or residual albuminuria [84,85]

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Those compounded options were meant as a temporary solution during a difficult time and were gradually phased out once the shortage ended

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It often shifts from one individual to the next