Food and Drug Administration approved the once to weekly semaglutide injection for chronic weight management in adults with a body mass index of 27 or greater, along with at least one other obesity related comorbidity such as high cholesterol or type 2 diabetes
Acute pancreatitis has been reported as a rare adverse event in clinical trials
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2017), while increased levels of cadaverine, trimethylamine-N-oxide and -tyramine were reported in the ulcerative colitis sub-group (Santoru et al
Semaglutide and tirzepatide are "upstream" they act on incretin receptors to influence appetite regulation, gastric emptying, and glucose-dependent insulin secretion
It is important to monitor for any unusual symptoms and seek medical attention if they occur