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NICE also recommends semaglutide for obesity only within specialist weight management services, alongside diet and physical activity support
They typically contain a combination of extracts, natural substances, and active ingredients like: Berberine Turmeric Brown algae extract Guarana Bee venom Caffeine Flaxseed extract L-carnitine 5-HTP Studies suggest that the ingredients listed above may have some effect on weight management when taken as oral supplements but this impact is small
The included trials did not provide enough data to compare GLP-1 analogues and sitagliptin regarding major cardiovascular events
Some patients may have received a prescription but ultimately were unable to fill it due to insurance coverage, cost-sharing requirements, or pharmacy-level barriers
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