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Both are synthesised by the body and available through diet, with supplementation increasingly used for cardiovascular health, mitochondrial disorders, and male fertility

Meanwhile, new potential peptide drugs are being discovered,24 suggesting promising but as-yet-undetermined directions in the treatment of common health concerns

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This makes them a safer alternative to more invasive weight loss procedures like surgery, with little to no downtime required

The SURPASS-CVOT trial demonstrated that tirzepatide reduced the risk of major adverse cardiovascular events by 20% compared to insulin glargine in patients with type 2 diabetes

doi: 10.1136/THORAX.55.4.283 235 AroraPKumarVBatraS