In contrast, preoperative GLP-2 plasma concentrations did not differ, but increased 3.4-fold within the first postoperative day in patients with PHLF, compared to an 1.5-times increase in patients who did not develop PHLF, resulting in 2.0-times higher GLP-2 level in PHLF on POD1 ( p = 0.008)
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In addition to being caused by physical stress, flattened nuclei may be indicative of genetic damage caused by toxicant-induced oxidative stress, peroxidation of cell membranes or genotoxicity 50