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41,42 GLP-1R is expressed in the cardiovascular system, and its knockout has implications for cardiovascular function

doi: 10.1056/NEJMoa072375 126 PandyaNDeMott-FribergRBowersCYBarkanALJaffeCA

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Liver & Kidney Stress, Organ Toxicity A controlled clinical study (treatment group: 1,200 mg IV twice a week for six weeks) comparing glutathione vs placebo found that 8 out of 16 participants developed deranged liver function tests