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Induction of apoptosis in AML by HA14-1, A cell-permeable organic compound identified by protein structure-based computer screening that binds the BH1 to BH3 surface pocket of Bcl-2
Standard ratios: 2mg peptide + 2ml water = 1mg/ml (1000mcg/ml) 5mg peptide + 2ml water = 2.5mg/ml (2500mcg/ml) 5mg peptide + 1ml water = 5mg/ml (5000mcg/ml) 10mg peptide + 2ml water = 5mg/ml (5000mcg/ml) How to choose: More water (2-3ml per vial): Easier to measure small doses accurately Larger injection volumes (0.2-0.3ml) Lasts longer (more injections per vial) Less water (1ml per vial): Higher concentration Smaller injection volumes (0.05-0.1ml) Fewer injections per vial Most people use 2ml of water for 5mg vials
The GIP receptor component may add additional cardiovascular benefits through effects on endothelial function, though this mechanism is less thoroughly characterized
Therefore, Boggio et al
Int J Biochem Cell Biol 71:111118 Gherman C, Braicu OL, Zanoaga O, Jurj A, Pileczki V, Maralani M, Drigla F, Braicu C, Budisan L, Achimas-Cadariu P, Berindan-Neagoe I (2016) Caffeic acid phenethyl ester activates pro-apoptotic and epithelial-mesenchymal transition-related genes in ovarian cancer cells A2780 and A2780cis
Per the telehealth consent published by OpenLoop Healthcare Partners, PC, the FDA does not approve, review, or evaluate compounded products for safety, effectiveness, or quality
