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Several factors can contribute to reduced levels of this vital antioxidant: 1
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It modulates the activity of metalloproteinases and their inhibitors, promoting the healing of various tissues such as skin, hair follicles, and bones
Upon intravenous injection, the nanoreactors can systemically activate the immune system, and nearly fully eradicate an aggressive osteosarcoma tumor inside a mouse model
This mechanism of Nrf2 pathway activation could similarly underlie bromelains antioxidant and anti-inflammatory effects in our ischemia-reperfusion model, given the parallel improvements observed in oxidative stress and inflammatory markers
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