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Some supplements also contain phyto-oestrogenic compounds (e.g., soy isoflavones, red clover), which could theoretically influence oestrogen-sensitive tissue, though evidence for clinical harm in endometriosis remains limited

The authors also thank Masayuki Goto, Manami Kaneko for advice

The latter is important from the aspect that PPIs are often bought over-the-counter and may represent additional bias

We like methylcobalamin because it reduces homocysteine levels and generates a crucial methyl donor called S-adenosyl methionine (SAMe)

doi: 10.1016/j.neuroscience.2013.10.038 154 YangYMaDXuWChenFDuTYueWet al

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