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702 Mutations in IDH impair its ability to catalyze the conversion of isocitrate to -KG and instead confer neomorphic activity, whereby it reduces -KG to D-2-hydroxyglutarate (D-2HG) in an NADPH-dependent manner

10.1016/j.jmb.2008.09.028 106 Martnez-MrquezA.Martnez-EstesoM

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Why Reference Standards Improve Documentation Confidence Reference standards can improve confidence when analytical comparisons are properly documented

Different pharmacies use different concentrations based on their formulation preferences, stability testing, and the dose ranges they intend to cover