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In utero exposure to topiramate (during first trimester of pregnancy) associated with increased risk of oral cleft birth defects
Moreover, the long-term effects are often best realized when combined with other healthy lifestyle choices, such as a balanced diet and regular exercise
Zheng, S
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In another study, semaglutide exhibited greater potency in activating GLP-1R compared to GLP-1, with an EC50 of 6.2 pM for semaglutide vs 16.2 pM for GLP-1 (95) (The variability in EC50 values among different studies for GLP-1 was not uncommon attributable to varying assay conditions)
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