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doi: 10.7150/IJBS.93120 96
The hypothalamus requires stable energy availability to maintain regular reproductive hormone production
Conditions characterized by increased ROS levels may require not only enhanced GSH action to maintain redox status, but also augmented energy supply and precursors to replace/enhance GSH content and/or transport it to the places where it is needed
Additionally, administration or overexpression of FGF21 reduces blood pressure in various preclinical models of hypertension (316318)
The presence of GLP-1 in the brain is linked to its ability to promote satiety and reduce food intake, which is beneficial in weight management and obesity treatment
The public evidence currently supports the first much better than the second
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