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[12] Post-marketing surveillance data from the FDA Adverse Event Reporting System (FAERS) indicate that serious hepatic adverse events with semaglutide are rare, though such spontaneous reporting systems have inherent limitations and cannot establish true incidence or definitive causality

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Short-acting GLP-1 receptor agonists including exenatide immediate-release (Byetta) should be injected within 60 minutes before morning and evening meals , and lixisenatide (Lyxumia) should be administered within 1 hour before any meal of the day