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While not classified as a controlled substance, it is regulated differently for research, therapeutic, and athletic contexts

The PPP branches after the first step of glycolysis and consumes the intermediate glucose 6-phosphate (G6P) to generate fructose 6-phosphate (F6P) and glyceraldehyde 3-phosphate (G3P) through the oxidative and non-oxidative branches of the PPP

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Because KPV apparently curbs NF-B and MAPK signaling and lowers pro-inflammatory cytokine release, it may help create conditions under which fibroblast activity and matrix deposition may continue with less inflammatory interference

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