Slopes for AP and NTS are not significantly different (p = 0.6623)
Metformin: a hopeful promise in aging research
Doctors are saying, Okay, well, take your GLP-1s and this is going to make you less motivated for food, but we somehow expect you to have more motivation to change your diet and to exercise. If its gonna dampen your desire to kind of eat, isnt it also going to dampen your desire, like that high you get from working out, or that [thought], Hey, I wanna be healthier, maybe I should go for a salad. If you think the only reason to eat better is to lose weight and something else is making you lose weight, that might actually give you inherently less motivation to eat better.
Water, herbal teas, and electrolyte drinks are ideal
Heartburn is also more likely Heartburn is already more common on oral semaglutide than on the injectable form, for reasons related to the SNAC absorption mechanism and slowed gastric emptying. Alcohol relaxes the lower oesophageal sphincter - the valve between the stomach and oesophagus - which makes reflux more likely
00:13:28 Sara Klockars Jen, would you want to comment on that, on the data we have