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other benefits of semaglutide include: Increasing insulin sensitivity, which enhances the cells use of glucose blood (i.e., sugar) Lowering type 2 diabetes risk Lowering blood pressure Reducing the risk of heart attack, stroke, kidney disease, diabetes and some cancers Improving cholesterol levels and reducing triglycerides (i.e., a type of fat that circulates in the blood contributing to arterial plaque build-up and stroke risks) Semaglutide Side Effects Common semaglutide side effects of semaglutide include swelling, redness, itching, or pain at the injection site